For you, if you want to combat aging at a cellular level
The powerful nutrients in NAD+ Cell Regenerator™ and Resveratrol Elite™ can:
Support youthful levels of NAD+, which is used in energy production
Help maintain already healthy blood pressure
Offer protection against oxidative stress
Promote brain health & cognitive function
Provide enhanced bioavailability* of resveratrol (10x), quercetin (62x) & fisetin (25x)
NAD+ Cell Regenerator™ and Resveratrol Elite™ combines 300 mg of NIAGEN® nicotinamide riboside with bioavailable forms of trans-resveratrol, quercetin, and fisetin to fight general fatigue and promote longevity with every dose by supporting heart, mind, and cellular health.
*Compared to unformulated nutrients
Ingredients:

Health benefits at a glance:
First of all, what is NAD+? It's a cellular coenzyme that’s found in every cell of our bodies. NAD+ is critical to healthy cellular energy, meaning it's necessary to create adenosine triphosphate (ATP), the compound the body uses for fuel. The levels of NAD+ decline with age.
NIAGEN® nicotinamide riboside can increase your levels of NAD+. Resveratrol may promote a variety of health and longevity mechanisms, quercetin can support heart and immune health, and fisetin can encourage your body to clear senescent cells.
This formula combines ultra-bioavailable forms of all four nutrients creating an unrivaled supplement for energy, vitality, and defense against cellular aging.
Why it works:
An age-related decline in cellular metabolism and energy production can lead to a feeling of fatigue and can also affect motivation negatively. NIAGEN® nicotinamide riboside found in NAD+ Cell Regenerator™ and Resveratrol Elite™ can increase cellular levels of NAD+, which is essential to normal cellular energy production.
Increasing NAD+ levels can also encourage normal cognitive function and contribute to maintaining blood sugar levels already within the normal range.
Life Extension® was among the first to point out the amazing health benefits of both resveratrol and later, NIAGEN® which is the first commercially available form of nicotinamide riboside.
NAD+ Cell Regenerator™ and Resveratrol Elite™ combines NIAGEN® nicotinamide riboside with trans-resveratrol, quercetin and fisetin.
Now, all of these powerful bioavailable longevity nutrients are available in a single, convenient anti-aging formula to support cellular metabolism, fight fatigue, help regulate genes that control aging, and much more.
The science behind the product:
Resveratrol's anti-aging benefits
Resveratrol is a polyphenol that can promote numerous health and longevity mechanisms, and it's a well-known supplement for anti-aging benefits. (1) Life Extension’s Resveratrol Elite™ formulas contain trans-resveratrol (from Japanese knotweed), the form associated with significant biological effects. (2-5)
It can promote healthy insulin sensitivity, support a healthy inflammatory response, and contributes to optimal endothelial function for a healthy cardiovascular system. (4,6,7)
Enhanced bioavailability of resveratrol
You’ve probably heard about research that red wine is good for you. Science has found that the grapes used to make red wine contain resveratrol. But ordinary resveratrol has low bioavailability.
This problem is solved with special delivery technologies that protect these nutrients once ingested, resulting in a massive boost in bioavailability. To maximize the absorption of trans-resveratrol, the formula also contains galactomannan fibers derived from fenugreek seeds.
This combination increases the bioavailability of Resveratrol Elite™ up to 10 times, ensuring higher levels of trans-resveratrol in the bloodstream and extended circulation compared to unformulated resveratrol.
Cardiovascular health and resveratrol
Resveratrol can promote heart health by protecting the body from oxidative stress at the cellular level. (8)
By inhibiting oxidative stress in the cardiovascular system, resveratrol can support endothelial health, which is essential for a long and healthy life. (9)
Brain function, glucose metabolism, and resveratrol
Furthermore, resveratrol's ability to support cerebrovascular blood flow suggests benefits for brain health and healthy cognition. Clinical evidence indicates that resveratrol can help maintain youthful neurological function.
Moreover, the same trial also showed that resveratrol may encourage healthy glucose metabolism, a vital aspect of overall well-being and longevity. (10)
NIAGEN® for fighting general fatigue
Nicotinamide riboside increases your body’s levels of the coenzyme NAD+, which is critical to healthy cellular function. (11)
In a randomized controlled trial published in 2017, older adults taking a daily dose of 250 mg of nicotinamide riboside had a 40% increase in NAD+ levels after just 30 days. (2)
Studies in preclinical models have shown that increasing NAD+ also promoted healthy metabolic and cognitive function. (3,4)
Improved resveratrol support with bioavailable quercetin
To further amplify the benefits of resveratrol, this supplement includes quercetin, a powerful phytonutrient that complements resveratrol. In a randomized clinical study, researchers found that quercetin formulated with fenugreek fibers (Bio-Quercetin) achieved serum levels up to 62 times higher than standard quercetin. Levels of free (unconjugated) quercetin were 18 times higher. (12)
Quercetin can promote both cardiovascular and endothelial health and support healthy blood pressure already within the normal range. (13,14)
It can also help combat oxidative stress, contributing to a balanced inflammatory response. Moreover, quercetin is well known for its strong immune-supporting properties. (15-17)
Bio-fisetin: Next-level fisetin absorption
By combining the phytonutrient fisetin with fenugreek fibers, it has been possible to create a formula that is up to 25 times more bioavailable than standard fisetin. Fisetin can help inhibit inflammation and induce autophagy. (18)
Elevate your fight against aging at the cellular level with a best-in-class formula
How to use:
Please take according to the dosage and use guidelines under supplement facts, or as recommended by a healthcare practitioner.
Serving size: 1 Capsule
Servings per Container: 30
Amount per Day (1 capsule): | %RI* | |
---|---|---|
Niacin from NIAGEN® Nicotinamide Riboside (300 mg) | 126 mg | 788 |
Resveratrol Elite™ Proprietary Blend: Providing 18% trans-resveratrol (10 mg) [from Japanese knotweed (root)], 35% galactomannans (19 mg) [from fenugreek (seed)] | 55 mg | ** |
Bio-Quercetin® phytosome [providing 5 mg quercetin from Japanese sophora concentrate (flower bud), phosphatidylcholine complex from sunflower (seed)] | 14,7 mg | ** |
Bio-Fisetin Proprietary Blend 18% fisetin (0.4 mg) [from wax tree extract (stem)], 35% galactomannans (0.77 mg) [from fenugreek (seed)] | 2,22 mg | ** |
*RI = EU reference intake **No RI available
INGREDIENTS:
Nicotinamide riboside chloride, capsule (hydroxypropylmethylcellulose), resveratrol from Japanese knotweed root extract (Fallopia japonica (Houtt.), galactomannans from fenugreek seed extract (Trigonella foenum-graecum L.), quercetin from Japanese sophora flower bud concentrate (Sophora japonica L.), sunflower lecithins, bulking agent (microcrystalline cellulose/cellulose gel), anti-caking agents (fatty acids, silicon dioxide [nano]), fisetin from wax tree extract (Toxicodendron succedaneum)
non-GMO
NIAGEN® is a registered trademark of ChromaDex, Inc., Patents see: www.ChromaDexPatents.com.
DIRECTIONS:
Take one (1) capsule daily, with or without food. Nicotinamide Riboside Chloride does not cause flushing.
WARNINGS:
- Keep out of reach of children.
- Do not exceed recommended daily dose.
- Do not purchase if outer seal is broken or damaged.
- Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
- A food supplement should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.
- Store tightly closed in a cool, dry place.
- Med Res Rev. 2019;39(5):1851-1891.
- Nutrient Delivery Academic Press; 2017:413-456. https://www.sciencedirect.com/science/article/pii/B9780128043042000111
- Chemistry Central Journal. 2011;5(88):1-6.
- Micronutrient Information Center. 2015;2018(04/23/2018)
- Mol Nutr Food Res. 2005;49(5):495-504.
- Biochim Biophys Acta. 2015;1852(6):1145-54.
- Obes Rev. 2016;17(12):1329-1340.
- Br J Pharmacol. 2020;177(6):1258-1277.
- Phytother Res. 2022
- Clin Nutr. 2021;40(3):820-829.
- Nat Commun. 2016;7:12948.
- ACS Omega. 2022;7(50):46825-46832.
- J Nutr. 2015;145(7):1459-63.
- Nutr Rev. 2020;78(8):615-626.
- Crit Rev Food Sci Nutr. 2020;60(11):1855-1868.
- Nutrients. 2020;12(9)
- Pharmacol Res. 2010;62(3):237-42.
6. J Nutr Sci. 2022;11:e74.
- J Nutr Sci. 2022;11:e74.