What is Creatine?

Creatine is a compound derived from amino acids, naturally present in meat and seafood. The human body also produces it, primarily in the liver and kidneys, using the amino acids L-arginine, glycine, and S-adenosylmethionine. 

Once produced, creatine is transported through the bloodstream to support energy production in cells across the body.

Each serving of Creatine Capsules contains 500 mg of easily absorbed creatine monohydrate.

Creatine in the Skeletal Muscles

95% of the body’s creatine is stored in skeletal muscles, with smaller amounts found in the brain and testes. 

Around two-thirds of this intramuscular creatine is converted into phosphocreatine, which serves as a phosphate reserve for the production of cellular energy (ATP). In healthy individuals, muscle creatine is continuously broken down and replenished at a rate of about 1 to 3 grams per day. (1,2)

Research shows that creatine supplementation can enhance muscle mass, strength, and performance across various age groups and types of physical activity. (1,2) It has been shown to improve both upper and lower body muscle strength. (3,4)

Creatine influences muscle tissue in several ways, and multiple mechanisms have been suggested to explain the enhanced exercise performance observed after creatine intake:

• Optimizing energy metabolism by maintaining higher levels of the body's energy currency, adenosine triphosphate or ATP (5)
  
• Promoting protein metabolism in muscle cells (6,7) 
• Inhibiting tissue damage by inhibiting oxidative stress (2,6,8)

Creatine Benefits with Ageing

Multiple clinical studies have shown that creatine positively impacts strength, body composition, and muscle performance in older adults, particularly when combined with resistance training. (1,2)

A systematic review found improvements in upper and lower body strength, physical performance, and body composition after 12 weeks of creatine supplementation alongside resistance exercise in healthy older individuals. (9) Creatine has even been shown to benefit non-exercising seniors. (10) 

Research reveals that the advantages of creatine extend beyond muscle health. Evidence suggests that creatine supplementation can support neurological and cognitive health, promote a healthy mood, and offer neuroprotective effects. (11,12)

Additionally, creatine has been reported to support healthy metabolism of lipids, glucose, bone, and homocysteine in older adults. (1)